Many vets will prefer to provide the injection at the vet's office. The recommended dosage of praziquantel varies according to body weight. Photo courtesy of CDC. Proper restraint of roaming dogs should be encouraged, along with regular treatment with Praziquantel Injection solution, following the dosing schedule aforementioned and precautions indicated below. 1 Andrews P. Pharmacokinetic Studies with Praziquantel Injection in Animals Using a Biological Assay. Praziquantel is primarily used against parasites known as cestodes (tapeworms). Lea & Febiger. The following medications can increase the blood levels of praziquantel: cimetidine (an antacid), ketoconazole (an antifungal), and itraconazole (another antifungal). Praziquantel is also available in combination with other single use oral dewormers as well as with more comprehensive monthly worm protection products. W.B. Cats: Taenia taeniaeformis and Dipylidium caninum. 154-165. ), Hydrocodone Bitartrate (Hycodan, Tussigon, Mycodone), Ivermectin (Ivomec, Heartgard 30, Acarexx, Iverheart Plus), Levetiracetam (Keppra, Keppra XR, Kepcet, Kerron, Kevtan, Levitaccord, Levitam), Meclizine Hydrochloride (Bonine, Antivert, Dramamine, UniVert, Vertin-21), Medications for Degenerative Arthritis in Dogs and Cats, S-Adenosylmethionine (SAMe, Denosyl, Novifit, Vetri-SAMe, Zentonil, Denamarin), Selegiline (L-Deprenyl) Hydrochloride (Anipryl, Eldepryl, Carbex), Tetracycline (Panmycin, Tetracap, Tetracyn, Sumycin, Tetralan), Trimethoprim-Sulfa (Bactrim, Tribrissen, Septra, Sulfatrim, Cotrim), Amoxicillin/Clavulanic Acid - Drug Information Sheet, Chlorpheniramine - Drug Information Sheet, Sulfadimethoxine - Drug Information Sheet, Trimethoprim Sulfa - Drug Information Sheet, Controlled Scientific Studies versus Scientific Research, Differences between Medical Devices and Drugs, Ebola Virus Outbreaks and Veterinary Considerations, Financial Assistance for Veterinary Bills, Imaging Tests (Radiology Options) for Pets, Internet Research: Gathering Information Efficiently and Wisely, Monkeypox in Humans: A Fact Sheet from the CDC, Monkeypox Infections in Animals: Guidelines from the CDC, Plague and How Avoid It in You or your Companion Animals, Postmortems in Pets are a Delicate Subject, SI and U.S. Standard Measurements: Conversion Confusion for Pet Owners, Veterinary Certifications: The Alphabet Soup of Specialists, Veterinary Clinical Trials and Research Projects, Veterinary Technicians Influence a Clinic's Success, Anne E. Katherman, DVM, DACVIM (Neurology), Bob Judd, DVM, DABVP (Equine Medicine), DABVP (Canine and Feline Practice), Carlye Rose, DVM, DABVP (Canine and Feline), DABVP (Feline), CVA, Centers for Disease Control and Prevention, Charlotte Means, DVM, DABVT (Pharmacology/Toxicology), DABT (Pharmacology/Toxicology), Christine Calder, DVM, DACVB (veterinary behaviorist, Dennis T. (Tim) Crowe, Jr., DVM, Diplomate ACVS Emeritus, Charter Diplomate ACVECC, FCCM, Jo-Anne Brenner, EMT-Tactical, NREMT-I, K9™ Medic Executive Director and Founder, Kersti Seksel, BVSc, MA, DACVB, FANZCVS, ECAWBM, Paul J. Mellor, BVMS, ECVIM-CA (Internal Medicine), Phyllis DeGioia, Veterinary Partner Editor, Sharon M. Gwaltney-Brant, DVM, PhD, DABT, DABVT, Thomas M. Donnelly, DVM, DACLAM, DABVP, DECAM. It is our policy not to give dosing information over the Internet. Studies on Sylvatic Echinococcosis, III. J Parasit 56 (6) 1141-1150. Praziquantel Injection has been tested in breeding and pregnant dogs and cats. Eggs may begin to be passed in the feces of the canid approximately 28 days later. The animal should be held in the clinic during this interval and all feces should be incinerated or autoclaved. No adverse effects were noted. We comply with the HONcode standard for trustworthy health information -, Warnings and cautions for Praziquantel Injection, Direction and dosage information for Praziquantel Injection. Saunders Co. 118-138. The safety index has been derived from controlled safety evaluations, clinical trials and prior approved use in foreign countries. The majority of tapeworms killed are digested and are not found in the feces. Fasting is not necessary prior to praziquantel use and oral praziquantel can be given with or without food. Praziquantel Injection is absorbed, metabolized in the liver and excreted via the bile into the digestive tract where its cestocidal activity is exerted1. The information contained here is for general purposes only and is not a substitute for advice from your veterinarian. Brand name products, combination products, and injections are available only through veterinarians as they are prescription drugs. The brand name of this product is Profender® and is available by prescription. In addition, for control of Echinococcus multilocularis, a program of regular treatment every 21 to 26 days may be indicated (see E. multilocularis section below). Laboratory efficacy studies have demonstrated the recommended dosage is 100% efficacious for removal of this tapeworm. Sodium Hypochlorite as an Ovicide for Echinococcus. Wounds: First Aid. Available for Android and iOS devices. Echinococcus multilocularis is a tapeworm species ordinarily considered to be found in wild canids, including foxes, coyotes and wolves. Transporting an Injured Pet: First Aid. The life cycle is completed after a canid consumes a rodent infected with cysts. What to Expect from your Pet’s Echocardiogram, Antifreeze Additives that are Taste Aversive to Protect Dogs and Cats, Breeding Information for People Who Want to Breed Dogs, Cardiopulmonary Resuscitation (CPCR): First Aid. Praziquantel is also effective against flukes. 7th Edition. Praziquantel is felt to be safe for use in pregnant patients. As of late 2007, praziquantel is also available in a topical combination with the anti-parasite drug emodepside. There is also a tablet which you can provide to your pet orally along with his food or with a treat. For medical emergencies or to report adverse reactions, call 1-800-759-3664.