Ⓒ 2020 About, Inc. (Dotdash) — All rights reserved. Large dosage of blue vervain may interfere with nervous system and cause adverse effects such as allergy, stupor, seizures, nausea, diarrhea, and vomiting. This article discusses…, Growing evidence points to certain dietary habits increasing or decreasing cancer risk. 2016;7:499. doi:10.3389/fphar.2016.00499. For more details, see our Privacy Policy. Side Effects & Safety Blue cohosh is LIKELY UNSAFE for adults when taken by mouth. However, none of those uses are supported by science. Anxiety, measured by movement through a maze, was also seen to improve. If used for tea, avoid spraying the herbs with pesticides or using chemical fertilizers. Self-treating any medical condition without input from a qualified doctor or avoiding the standard care of treatment is unadvised and may put you in harm's ways. It’s important to…, Mayo is a popular condiment for sandwiches and often used as a base for salad dressings and sauces. This suggests that vervain polysaccharides may one day be used to help isolate and control tumors in people with colorectal cancer, improving survival. In a 2016 study, different parts of the V. officinalis were able to eradicate 24 strains of disease-causing bacteria. According to the research, extracts derived from the stem of V. officinalis were able to kill Staphylococcus aureus and Pseudomonas aeruginosa in the test tube more effectively that the antibiotic amoxicillin. There are no reported side effects of vervain, though it is thought that due to its purgative effects, excess dosages may lead to vomiting. Vervain is used in traditional medicine to treat infections and abdominal pain and to promote milk production in breastfeeding women. Side Effects It is recommended to avoid vervain in pregnancy as it is uterine tonic, may be used in labour. Vervain is generally recognized as safe (GRAS) by the Food and Drug Administration (FDA). These effects are attributed to a sugar molecule in vervain, known as verbenalin, which is believed to have psychoactive properties. A 2006 study from Spain found that an extract of V. officinalis, applied topically in rats, was as effective in relieving edema (swelling) as traditional anti-inflammatory drugs, but it was far less able to relieve pain., Verbena tea has long been believed to have a calming effect that can help relieve stress and promote sleep. A 2016 study published in the Frontiers of Pharmacology reported that an extract of V. officinalis, prescribed at a dose of 100 to 500 milligrams per kilogram, reduced the frequency and duration of tonic-clonic seizures in mice.. Vervain’s extract and essential oils may provide other potential health benefits, such as: Vervain is a popular remedy due to its multiple plant-beneficial compounds. This can actually hurt the kidneys more than help, especially over the long term. Vervain is a perennial plant from the mint family, identified by little purple-blue flowers and small spikes around the bud. Like many herbal Sign up for our Health Tip of the Day newsletter, and receive daily tips that will help you live your healthiest life. Anecdotal evidence suggests that blue vervain tea was used for insomnia. List of various diseases cured by Vervain. Vervain is generally recognized as safe by the FDA. While it is unclear if the same effect would be rendered in humans, it does suggest that V. officinalis may exert a positive influence on the central nervous system and adrenal glands (which produce stress hormones). The whole plant is also used to treat abdominal pain and to protect against the evil eye, which is believed to cause misfortune or injury (21). There’s no cure for Alzheimer’s, but there…. One study from China found that mice treated with verbenalin injections experienced no changes in either the structure or function of their kidneys compared to mice provided a placebo.. Antibiotic resistance is a growing global concern. Vervain is also traditionally used as a galactagogue, a substance that increases milk production in breastfeeding women. Even after many […] Anti-inflammatory and analgesic activity of the topical preparation of Verbena officinalis L. J Ethnopharmacol. Trop J Pharm Res. Vervain extract may benefit certain neurological or brain-related conditions. While it’s usually well tolerated, there have been reports of side effects (22). Capsules are available in doses ranging from 150 milligrams to 1,000 milligrams. Verbena officinalis is a perennial plant with delicate, jagged leaves and small, five-petaled blossoms. doi:10.1016/j.sjbs.2015.10.006. Although there have been few studies investigating these effects in humans, there is evidence that V. officinalis not only reduces anxiety and insomnia but may prevent the occurrence of epileptic seizures. Excess stress is a common problem for many people. Jin C, Liu X, Ma D, et al. The safety of this medicinal herb for children or for people with severe liver or … Dennis Sifris, MD, is an HIV specialist and Medical Director of LifeSense Disease Management. Results have been largely mixed. In traditional Chinese medicine, it is known as mǎ biān cǎo. Vervain contains over 20 beneficial plant compounds, including iridoid glycosides, flavonoids, and triterpenoids, which may be responsible for its purported benefits (2). These claims were largely fostered by research which showed that polysaccharides (a type of long-chain carbohydrate) in vervain altered the activity of colorectal cancer cells in test tubes. Researchers attributed this anti-tumor activity to verbenosides A and B — two types of glycosides — and triterpenoids (3). Large dosage of blue vervain may interfere with nervous system and cause adverse effects such as allergy, stupor, seizures, nausea, diarrhea, and vomiting. Miao, M.; Guo, L.; Yan, X. et al. Potential Side Effects of Vervain There are no reported side effects of vervain, though it is thought that due to its purgative effects, excess dosages may lead to vomiting. The flowers are also used as a garnish in cocktails and alcoholic beverages. It should not be used while pregnant as it may stimulate contractions. Before using a vervain tincture, always apply a little to the skin and wait an hour to see if a rash develops. It is not known if vervain interacts with other drugs. In a mouse study, high doses of vervain extract of 18 grams per pound (40 grams per kg) of body weight inhibited tumor growth by more than 30%, compared with controls. It should not be used while pregnant as it may stimulate contractions. This effect was first described in the 1652 book "The English Physician" in which vervain was used as a tea to treat "over-enthusiasm.". Severe anaphylactic reactions are rare. 2017;16 (10):2387-94. doi:10.4314/tjpr.v16i10.11. All rights reserved. A study in rats determined that doses of 0.04–0.22 grams per pound (0.1–0.5 grams per kg) of body weight of vervain extract had an anxiety-reducing effect comparable to diazepam, a popular drug used to reduce anxiety (11). Compounds in vervain essential oil, such as citral, are known to possess antimicrobial activities. Thus, pregnant women should avoid all vervain-containing products (23). Thank you, {{form.email}}, for signing up. As an herb, V. officinalis is considered safe for consumption with a few side effects, namely indigestion and gas. According to the National Center for Complementary and Integrative Health, some Chinese herbal products are safe, but others are not. There have been reports of some products being contaminated with drugs, pesticides, or heavy metals or not containing the listed ingredients. Additionally, it’s unknown if compounds from the plant could excrete into breast milk.

blue vervain side effects

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